A number of Republicans I've met are pro cannabis, or at least pro CBD. I suspect that if the demographics were analyzed, the higher-income Republicans would tend to vote "No" on legalization, and the lower-income ones "Yes".

Trump just endorsed it (for "stopping fentanyl laced weed" reasons, but nevertheless). I think that might just be enough to move the needle in favor of it passing.

https://www.marijuanamoment.net/another-poll-shows-florida-marijuana-legalization-ballot-initiative-just-shy-of-support-for-passage/

Republican Party says vote NO (not a surprise)

https://floridaphoenix.com/2024/05/06/fl-republican-party-officially-comes-out-against-initiative-to-legalize-adult-cannabis/

DeSantis predicts NO:

https://www.marijuanamoment.net/desantis-says-florida-voters-will-reject-radical-marijuana-ballot-measure-claiming-it-would-reduce-the-quality-of-life/