The current district 2 supervisor Catherine Stefani has been elected to the state assembly. Stefani will need to resign from her supervisor seat in December, allowing Mayor London Breed to appoint her replacement, according to https://sfstandard.com/2024/11/05/sf-election-2024-ad19-catherine-stefani-david-lee/

I am not sure which potential appointees meet residency or other requirements, or indeed who the most likely potential appointees are, so I will start with Breed (who likely doesn't live in the district, but always could have moved in anticipation) and living predecessors to Stefani as supervisor. Bet against those who don't make sense, add more options that do!