This market will resolve YES if no humans are born in a "normal" way for a year before 2050. By normal, I mean that the pregnancy is carried to term by a human person. This means that pregnancies by trans men and (potentially) trans women qualify as normal. In contrast, pregnancies carried by artificial wombs are not normal. Likewise, if human consciousness is only reproduced through brain emulation, this also qualifies as not normal. Finally, if humans cease to be able to give birth for a year, either through complete infertility or extinction, this market will resolve YES.